The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November of 2021 in South Africa and Botswana as well as in a sample from a traveler from South Africa in Hong Kong 1,2 . Between 1 and 7 March . The latest Tweets from Florian Krammer (@florian_krammer). Thread by @florian_krammer: 1) What do I think about Omicron now that some neutralization data is available? — Florian Krammer (@florian_krammer) November 27, 2021 Researchers from South Africa and the other countries that have detected Omicron this week are already sharing genetic sequences on public platforms, driving much of the scientific discussion about this variant. Tweet from florian_krammer at November 27, 2021 at 03:04AM Posted Sunday 28th of November, 2021 at 9:49:20 AM by Jeff 1) My gut feeling from hearing of Omicron cases in Botswana, ex-Malawi, ex-Egypt (2 now it seems) and in South Africa is, that the variant was flying under the radar in undersequenced countries for some time until Botswana and . 357 Followers, 190 Following. My impression hasn't change. The omicron variant, however, is more transmissible than previous variants and is probably driving the current surge. Protection from severe disease 1) My gut feeling from hearing of Omicron cases in Botswana, ex-Malawi, ex-Egypt (2 now it seems) and in South Africa is, that the variant was flying under the radar in undersequenced countries for some time until Botswana and South Africa detected it and sounded the alarm. Lab results have shown 32 mutations with Spike proteins that are different from the ones our vaccines are made to target. "We have people working the whole weekend again," says Florian Krammer, a vaccine researcher at the Icahn School of Medicine at Mount Sinai. "This does not bode well for vaccine-induced immunity," virologist Florian Krammer told Science. @florian_krammer Nov 27, 2021 1) My gut feeling from hearing of Omicron cases in Botswana, ex-Malawi, ex-Egypt (2 now it seems) and in South Africa is, that the variant was flying under the radar in undersequenced countries for some time until Botswana and South Africa detected it and sounded the alarm. We are talking about Florian Krammer von the Icahn School of Medicine at Mount Sinai in New York. @florian_krammer is a worried virologist; "The mutations in Omicron which seem to wipe out the majority of neutralizing antibody epitopes are very worrisome. Florian Krammer, PhD, comments on the Omicron variant causing more infections in people who have recovered from an earlier bout with the virus, a sign that the new variant is able to escape at least some of the immune system's defenses. Omicron coronavirus cases are doubling roughly every three days in the Gauteng province, a populous economic hub in South Africa. Florian Krammer is a professor at the department of microbiology at the Icahn School of Medicine at Mount Sinai. "If we saw ladderlike evolution, we would know we need an Omicron vaccine now," Florian Krammer, a flu-virus expert at the Icahn School of . Omicron Variant Spreading Twice as Quickly as Delta in South Africa. Since then, B.1.1.529 has been detected globa … and Omicron variants. Twitter: @florian_krammer WHO meeting on COVID-19 Vaccines Research December 6th 2021 'regular vaccine' 'regular vaccine' 'regular vaccine' 'Beta/B.1.351 vaccine' What will happen after a booster dose with an Omicron specific vaccine? @florian_krammer 27 Nov 1) My gut feeling from hearing of Omicron cases in Botswana, ex-Malawi, ex-Egypt (2 now it seems) and in South Africa is, that the variant was flying under the radar in undersequenced countries for some time until Botswana and South Africa detected it and sounded the alarm. Thread by @florian_krammer: 1) What do I think about Omicron now that some neutralization data is available? Florian Krammer Influenza virus infections remain a high risk to human health, causing up to 650,000 deaths worldwide every year, with an enormous burden on the health care system. Florian Krammer The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November of 2021 in South Africa and Botswana as well as. Adaptive immune responses to SARS-CoV-2 . Since then, B.1.1.529 has been detected globa … NIAID/NIH. The government is meeting with experts and state governors on Wednesday for the big Corona summit and is planning further opening steps. Posts are my own. A booster tailored to Omicron would likely offer better protection, vaccinologist Florian Krammer of the Icahn School of Medicine at Mount Sinai told Science earlier this week, and vaccine manufacturers, eyeing a new market, are doing the preliminary work to concoct new formulations. The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November 2021 in South Africa and Botswana, as well as in a sample from . "This is super interesting because it would almost. — Florian Krammer (@florian_krammer) November 27, 2021. Protection from severe disease A cell infected with a variant strain of the coronavirus. Florian Krammer Mount Sinai Professor in Vaccinology Icahn School of Medicine at Mount Sinai WHO Global Consultation - Developing a framework for evaluating new COVID-19 vaccines February 23rd, 2022. P hysicians around the world have . He has published . Florian Krammer, at Mount Sinai's Icahn School of Medicine, told the New York Times: "The difference between the two age groups is striking," Those in the younger age group receive a 10 microgram dose of the vaccine, compared with 12 to 17-year-olds who receive a 30 microgram dose, which could explain some of the discrepancy in the . Viruses, viruses, viruses and vaccines. Florian Krammer Mount Sinai Professor in Vaccinology Icahn School of Medicine at Mount Sinai WHO Global Consultation - Developing a framework for evaluating new COVID-19 vaccines February 23rd, 2022. "That's not what we have seen." My impression hasn't change. See tweets, replies, photos and videos from @HedtrichLab Twitter profile. Combined with the apparent fitness of the virus, this could be a problem" "It doesn't matter if something needs to be done at 10 p.m., it's getting done." As with earlier variants, a handful of countries are providing the world with most of the early data. The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November of 2021 in South Africa and Botswana as well as in a sample . Currently Prof. Krammer holds a position as a Professor of Vaccinology at the Department of Microbiology at the Icahn School of Medicine at Mount Sinai. There is now a lot to do to get a better idea of the risk this virus variant poses. We seem to see a drastic reduction in neutralizing activity, far . New York, NY Prof. Dr. Florian Krammer Prof. Krammer is the Principal Investigator of the Sinai-Emory Multi-Institutional Collaborative Influenza Vaccine Innovation Center (SEM-CIVIC). So next Saturday 3G will apply again in the catering and hotel industry. and Omicron variants. The coronavirus vaccine made by Pfizer-BioNTech is much less effective in preventing infection in children ages 5 to 11 years than in older adolescents or adults, according to a large new set of data collected by health officials in New York State — a finding that has deep ramifications for these children and their parents.. The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November 2021 in South Africa and Botswana, as well as in a sample from . The study, led by Alex Sigal, a virologist at the Africa Health Research Institute in Durban, South . Combined with the apparent fitness of the virus, this could be a problem. Advocate for #WomenInScience A booster tailored to Omicron would likely offer better protection, vaccinologist Florian Krammer of the Icahn School of Medicine at Mount Sinai told Science earlier this week, and vaccine manufacturers, eyeing a new market, are doing the preliminary work to concoct new formulations. RELATED: 3 Signs You May Already Have Had COVID-19 Experts shared that Omicron's many mutations might make it more likely to evade immunity. Replying to @florian_krammer I missed longcovid on slide minute 50:00. Government statistics show 399,820 people tested positive for SARS-CoV-2 in the UK between 5 and 11 March, an increase of 143,956 (56.3 per cent) on the previous seven days. Adaptive immune responses to SARS-CoV-2 . — Florian Krammer (@florian_krammer) November 27, 2021 . Pan-sarbecovirus vaccine A consortium of #international #academic centers partnering to conduct systems #vaccinology studies in #newborns and infants. From left: Florian Krammer, PhD, Adolfo García-Sastre, PhD, and Peter Palese, PhD Microbiologists at the Icahn School of Medicine at Mount Sinai, who created the first and most reliable test to determine whether an individual has antibodies to SARS-CoV-2, have been monitoring the virus since it began circulating in Wuhan, China, in late 2019. noted Florian Krammer, an immunologist at the Icahn School of . — Florian Krammer (@florian_krammer) December 8, 2021. Building a panel for measuring virus neutralization Variant-proof SARS-CoV-2 vaccine •Wild type SARS-CoV-2 •A selection of VoCs and VoIs •BA.1 and BA.2 (Omicron) •To probe the extremes •SARS-CoV-1 •RaTG13 •WIV •Artificial escape mutants •E.g. Yes a 4th dose of current vaccine may not change much in terms of preventing severe illness and death but it could reduce the risk of longcovid a little bit more, especially when there is a high chance to get the infection now in Austria. 3) The mutations in Omicron which seem to wipe out the majority of neutralizing antibody epitopes are very worrisome. Virologist Florian Krammer spoke in "ZiB2" about the omicron situation in Austria and explained when and how the measures could be lifted. Florian Krammer, at Mount Sinai's Icahn School of Medicine, . V3=vaccinated three times Professor at the Department of Microbiology Icahn School of Medicine at Mount Sinai. Views are our own. The real-world impact is hard to predict, but the effect is big enough that protection against infection might be quite low, says Florian Krammer, a virologist at Mount Sinai's Icahn School of . Currently, the Pfizer dosage for children aged 5 to 11 is 10 micrograms, and for children and adolescents aged 11 to 17 it is 30 micrograms. . Corona pandemic in Austria: virologist warns of impending omicron wave The native of Styria is also in demand in the coronavirus pandemic. "If we saw ladderlike evolution, we would know we need an Omicron vaccine now," Florian Krammer, a flu-virus expert at the Icahn School of Medicine at Mount Sinai, told me. PMS20 (Schmidt et al., NEJM, 2021) •Mutants from yeast libraries (Jesse Bloom lab) •Etc. Prof. Dr. Florian Krammer. Unlike the widespread Alpha and Delta variants which medical professionals assured vaccines are effective against, it looks like Omicron is a bit different. Currently Prof. Krammer holds a position as a Professor of Vaccinology at the Department of Microbiology at the Icahn School of Medicine at Mount Sinai. Florian Krammer is a professor at the department of microbiology at the Icahn School of Medicine at Mount Sinai. The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November of 2021 in South Africa and Botswana as well as in a sample from a traveler from South Africa in Hong Kong 1,2 . Since 2010 he has been researching flu vaccines and vaccines against Ebola viruses. Omicron, for instance, wasn't an offshoot of Delta. Fact check:Most of the world is vaccinated against COVID-19, contrary to online claims "The booster vaccinations do not have a negative impact on the immune system," Florian Krammer, an . He said on Twitter that his opinion of Omicron has not changed following the . Resilience Stories (Live!) Omicron, for instance, wasn't an offshoot of Delta. Doctors hope Omicron causes milder cases of Covid — but it's still too early to say. The Pfizer vaccine is the only Covid shot authorized for that age . He said on Twitter that his opinion of Omicron has not changed following the results. 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